产品货号：
Z21701
中文名称：
MYD88抗体
英文名称：
Anti-MYD88 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MYD88 Antibody |
| 指标别名 | MYD88;MYD88D |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,IF,ICC,FCM,ELISA(Cap) |
| 基因名称 | MYD88 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MyD88 recombinant protein (Position:A44-F264).Human MyD88 shares 84% and 83% amino acid (aa) sequences identity with mouse and rat MyD88,respectively. |
| 实际分子量 | 33KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88),is a protein that,in humans,is encoded by the MYD88 gene.MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs).And it is mapped on 3p22.2.MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter.The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP.Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death,and do so in a way that might not compromise tissue repair or host defense against pathogens. |
| Uniprot ID | Q99836 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | myeloid differentiation primary response 88 |
| 蛋白名全称 | Myeloid differentiation primary response protein MyD88 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400Human ELISA(Cap) 1:50～1:200 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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